Eficacia pronóstica de la relación Plaquetas/Linfocitos y la relación Neutrófilos/Linfocitos en pacientes con cáncer gástrico

Joselyn Macarena López Altamirano; Daniela Alexandra Rosero Freire

doi:10.56294/saludcyt2023232

Autores/as

Joselyn Macarena López Altamirano Universidad Técnica de Ambato, Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador https://orcid.org/0000-0002-3212-2710
Daniela Alexandra Rosero Freire Universidad Técnica de Ambato, Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador https://orcid.org/0000-0002-4384-4081

DOI:

https://doi.org/10.56294/saludcyt2023232

Palabras clave:

NLR, PLR, cáncer gástrico, inflamación, pronóstico

Resumen

El cáncer representa la principal causa de muerte antes de los 70 años. El cáncer gástrico (CG) es responsable de 1 de cada 13 muertes alrededor del mundo y es predominante en hombres. La inflamación se encuentra estrechamente relacionada con el cáncer, debido a que activa varias células sanguíneas como neutrófilos, linfocitos, plaquetas, etc. Se realizó una revisión bibliográfica con la finalidad de recopilar y analizar estudios referentes a la eficacia pronóstica de la proporción neutrófilos /linfocitos (NLR) y la proporción plaquetas/linfocitos (PLR) en pacientes con cáncer gástrico. Tras el análisis, varios estudios indicaron que valores elevados tanto de NLR como de PLR muestran un mal pronóstico. Sin embargo, sugerimos que es necesario la realización de más investigaciones que permitan obtener valores de corte de acuerdo con la estadificación del CG, para que sea una herramienta de ayuda en el diagnóstico y pronóstico del mismo.

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