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Mean platelet volume and its close relationship with septic hospital infections

By
Daniela Alexandra Rosero Freire ,
Daniela Alexandra Rosero Freire

Universidad Técnica de Ambato. Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador

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Stephanie Pamela Urvina Paredes ,
Stephanie Pamela Urvina Paredes

Universidad Técnica de Ambato. Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador

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Abstract

Introduction: the average platelet volume is obtained from the blood count, considered as a low-cost and easily accessible biomarker, available in all medical units. It is considered a biomarker that indicates inflammation, thrombosis, and endothelial injury, while foreign studies have shown encouraging advances in diseases with prothrombotic and immunoinflammatory components.
Objective: to establish the relationship of mean platelet volume with hospital septic infections.
Methodology: information sources available in the Pubmed, Medicgraphic, and SciELO databases were consulted, as well as the Google Scholar search engine. Publications in both English and Spanish were included, with a maximum of 5 years prior to the topic of interest.
Results: Original articles were analyzed in which populations of neonates and adults with sepsis are analyzed. Populations of newborns reflected a high value of MPV in the first 24 hours, proving to be an early predictive marker in the diagnosis of neonatal sepsis, while population studies in adults reflected a much higher MPV in septic patients who later died. in relation to those who survived, being also considered a predictor of mortality.
Conclusions: it is evident that MPV is closely related to sepsis since it increases progressively during infection, constituting a biomarker for early prediction and poor prognosis in sepsis.

How to Cite

1.
Rosero Freire DA, Urvina Paredes SP. Mean platelet volume and its close relationship with septic hospital infections. Salud, Ciencia y Tecnología [Internet]. 2023 Apr. 17 [cited 2024 Jul. 15];3:250. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/250

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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