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Emerging Technologies in Industrial Microbiology: From Bioengineering to CRISPR-Cas Systems

By
Umar Farooq ,
Umar Farooq

Teerthanker Mahaveer University, Department of Microbiology, Moradabad, Uttar Pradesh, India

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Malathi Hanumanthayya ,
Malathi Hanumanthayya

Department of Life Science, School of Sciences, JAIN (Deemed-to-be University), Bangalore, India

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Izharul Haq ,
Izharul Haq

Assistant Professor, School of Life and Basic Sciences, Jaipur National University, Jaipur, India

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Abstract

Synthetic biology advancements have led to the emergence of "engineering biology" via equivalence and platform base on hierarchical, orthogonal, and modularized biological system. Utilizing bioparts found in sequence databases, genome engineering (GE) is required to create synthetic cells with the appropriate functionality. The CRISPR system, one of several tools, is modularly made up of Cas nuclease and guide RNA, making it simple to modify the GE at will. To correctly modify the GE at the distinct nucleotide level, many techniques have recently been devised. The CRISPR-Cas (CC) system has also been expanded to molecular diagnostics for nucleic acids and pathogen identification, together with viruses that cause illness. Furthermore, metabolic biotechnology is expanding to find the target of CC methodology, which can exactly regulate the production of certain genes in cells. In the present article, we evaluate the current state of several CC technology that may be used in synthetic biology and talk about how artificial biology and CC technology have evolved in the field of microbiology.

How to Cite

1.
Farooq U, Hanumanthayya M, Haq I. Emerging Technologies in Industrial Microbiology: From Bioengineering to CRISPR-Cas Systems. Salud, Ciencia y Tecnología [Internet]. 2023 Jun. 13 [cited 2024 Apr. 22];3:406. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/406

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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