Influencia de los avances en ingeniería de tejidos y medicina regenerativa en el progreso y la evolución de la salud
Artículo revisado por pares
Enviado: 08-06-2023
Revisado: 30-06-2023
Aceptado: 01-08-2023
Publicado: 02-08-2023
Editor: Dr. William Castillo González, https://orcid.org/0000-0003-3007-920X
Editor: Fasi Ahamad Shaik, https://orcid.org/0000-0002-1216-5035
DOI:
https://doi.org/10.56294/saludcyt2023452Palabras clave:
Ingeniería de tejidos, Medicina regenerativa, Bioimpresión 3D, Bioimpresión 3D de tejidos y órganos, biomateriales e interacciones celularesResumen
El área de la terapia regenerativa experimentará una revolución gracias a la bioimpresión 3D, que encierra un enorme potencial para la bioimpresión de tejidos y órganos artificiales. La presente investigación explora las posibles sinergias entre la bioimpresión 3D y los avances actuales en ingeniería de tejidos y medicina regenerativa. Antes de que la bioimpresión 3D se utilice de forma generalizada en estructuras organotípicas para la medicina regenerativa, hay que resolver una serie de obstáculos. Esto supone una importante carga para la sociedad en lo que se refiere a la atención a las personas con órganos deteriorados y enfermedades debilitantes. Los investigadores y expertos médicos están desarrollando medicamentos y tecnología capaces de reparar tejidos e incluso generar otros nuevos para resolver este problema. La ingeniería de tejidos y la medicina regenerativa se esfuerzan por crear nuevos tejidos y órganos y, al mismo tiempo, curar los dañados o enfermos mediante la fusión de la tecnología y los principios biológicos. Los avances sustanciales en estos campos tienen una influencia sustancial en la bioimpresión 3D de tejidos y órganos. El ámbito de la medicina regenerativa podría experimentar una transformación radical gracias al uso de la bioimpresión 3D, que permite construir nuevos tejidos y órganos. En este artículo se investiga la relación entre los últimos avances en ingeniería de tejidos, bioimpresión 3D y medicina regenerativa. Antes de que la bioimpresión 3D pueda utilizarse ampliamente para producir estructuras organotípicas destinadas a la medicina regenerativa, es preciso superar una serie de problemas.
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Shafiee A, Atala A. Tissue engineering: toward a new era of medicine. Ann Rev Med. 2017;68:29-40. https://doi.org/10.1146/annurev-med-102715-092331
Mantha S, Pillai S, Khayambashi P, Upadhyay A, Zhang Y, Tao O, Pham HM, Tran SD. Smart hydrogels in tissue engineering and regenerative medicine. Materials. 2019;12(20):3323. https://doi.org/10.3390/ma12203323
Sultankulov B, Berillo D, Sultankulova K, Tokay T, Saparov A. Progress in the development of chitosan-based biomaterials for tissue engineering and regenerative medicine. Biomolecules. 2019;9(9):470. https://doi.org/10.3390/biom9090470
Dzobo K, Thomford NE, Senthebane DA, Shipanga H, Rowe A, Dandara C, Pillay M, Motaung KSCM. Advances in regenerative medicine and tissue engineering: innovation and transformation of medicine. Stem Cells Int. 2018;2018. https://doi.org/10.1155/2018/2495848
Pina S, Ribeiro VP, Marques CF, Maia FR, Silva TH, Reis RL, Oliveira JM. Scaffolding strategies for tissue engineering and regenerative medicine applications. Materials. 2019;12(11):1824. https://doi.org/10.3390/ma12111824
Vial S, Reis RL, Oliveira JM. Recent advances using gold nanoparticles as a promising multimodal tool for tissue engineering and regenerative medicine. Curr Opin Solid State Mater Sci. 2017;21(2):92-112. https://doi.org/10.1016/j.cossms.2016.03.006
Deshmukh K, Kovářík T, Křenek T, Docheva D, Stich T, Pola J. Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review. RSC Adv. 2020;10(56):33782-33835. https://doi.org/10.1039/D0RA04287K
Arjmand B, Goodarzi P, Mohamadi-Jahani F, Falahzadeh K, Larijani B. Personalized regenerative medicine. Acta Med Iran. 2017:144-149.
Yadid M, Feiner R, Dvir T. Gold nanoparticle-integrated scaffolds for tissue engineering and regenerative medicine. Nano Lett. 2019;19(4):2198-2206. https://doi.org/10.1021/acs.nanolett.9b00472
Shin K, Acri T, Geary S, Salem AK. Biomimetic mineralization of biomaterials using simulated body fluids for bone tissue engineering and regenerative medicine. Tissue Eng Part A. 2017;23(19-20):1169-1180. https://doi.org/10.1089/ten.tea.2016.0556
Xu M, Qin M, Cheng Y, Niu X, Kong J, Zhang X, Huang D, Wang H. Alginate microgels as delivery vehicles for cell-based therapies in tissue engineering and regenerative medicine. Carbohydr Polym. 2021;266:118128. https://doi.org/10.1016/j.carbpol.2021.118128
Liu S, Yu JM, Gan YC, Qiu XZ, Gao ZC, Wang H, Chen SX, Xiong Y, Liu GH, Lin SE, McCarthy A. Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications. Mil Med Res. 2023;10(1):1-30. https://doi.org/10.1186/s40779-023-00448-w
Liu N, Ye X, Yao B, Zhao M, Wu P, Liu G, Zhuang D, Jiang H, Chen X, He Y, Huang S. Advances in 3D bioprinting technology for cardiac tissue engineering and regeneration. Bioact Mater. 2021;6(5):1388-1401. https://doi.org/10.1016/j.bioactmat.2020.10.021
Faramarzi N, Yazdi IK, Nabavinia M, Gemma A, Fanelli A, Caizzone A, Ptaszek LM, Sinha I, Khademhosseini A, Ruskin JN, Tamayol A. Patient‐specific bio-inks for 3D bioprinting of tissue engineering scaffolds. Adv Healthc Mater. 2018;7(11):1701347. https://doi.org/10.1002/adhm.201701347
Pang C, Ibrahim A, Bulstrode NW, Ferretti P. An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing. Int Wound J. 2017;14(3):450-459. https://doi.org/10.1111/iwj.12735
Savoji H, Godau B, Hassani MS, Akbari M. Skin tissue substitutes and biomaterial risk assessment and testing. Front Bioeng Biotechnol. 2018;6:86. https://doi.org/10.3389/fbioe.2018.00086
Goodarzi P, Falahzadeh K, Nematizadeh M, Farazandeh P, Payab M, Larijani B, Tayanloo Beik A, Arjmand B. Tissue-engineered skin substitutes. In: Cell Biology and Translational Medicine, Volume 3: Stem Cells, Biomaterials, and Tissue Engineering, pp.143-188. DOI: 10.1007/5584_2018_226
Gungor-Ozkerim PS, Inci I, Zhang YS, Khademhosseini A, Dokmeci MR. Bioinks for 3D bioprinting: an overview. Biomater Sci. 2018;6(5):915-946. https://doi.org/10.1039/C7BM00765E
Li X, Liu B, Pei B, Chen J, Zhou D, Peng J, Zhang X, Jia W, Xu T. Inkjet bioprinting of biomaterials. Chem Rev. 2020;120(19):10793-10833. https://doi.org/10.1021/acs.chemrev.0c00008
Shafiee A, Atala A. Tissue engineering: toward a new era of medicine. Ann Rev Med. 2017;68:29-40. https://doi.org/10.1146/annurev-med-102715-092331
Mantha S, Pillai S, Khayambashi P, Upadhyay A, Zhang Y, Tao O, Pham HM, Tran SD. Smart hydrogels in tissue engineering and regenerative medicine. Materials. 2019;12(20):3323. https://doi.org/10.3390/ma12203323
Sultankulov B, Berillo D, Sultankulova K, Tokay T, Saparov A. Progress in the development of chitosan-based biomaterials for tissue engineering and regenerative medicine. Biomolecules. 2019;9(9):470. https://doi.org/10.3390/biom9090470
Dzobo K, Thomford NE, Senthebane DA, Shipanga H, Rowe A, Dandara C, Pillay M, Motaung KSCM. Advances in regenerative medicine and tissue engineering: innovation and transformation of medicine. Stem Cells Int. 2018;2018. https://doi.org/10.1155/2018/2495848
Pina S, Ribeiro VP, Marques CF, Maia FR, Silva TH, Reis RL, Oliveira JM. Scaffolding strategies for tissue engineering and regenerative medicine applications. Materials. 2019;12(11):1824. https://doi.org/10.3390/ma12111824
Vial S, Reis RL, Oliveira JM. Recent advances using gold nanoparticles as a promising multimodal tool for tissue engineering and regenerative medicine. Curr Opin Solid State Mater Sci. 2017;21(2):92-112. https://doi.org/10.1016/j.cossms.2016.03.006
Deshmukh K, Kovářík T, Křenek T, Docheva D, Stich T, Pola J. Recent advances and future perspectives of sol–gel derived porous bioactive glasses: a review. RSC Adv. 2020;10(56):33782-33835. https://doi.org/10.1039/D0RA04287K
Arjmand B, Goodarzi P, Mohamadi-Jahani F, Falahzadeh K, Larijani B. Personalized regenerative medicine. Acta Med Iran. 2017:144-149.
Yadid M, Feiner R, Dvir T. Gold nanoparticle-integrated scaffolds for tissue engineering and regenerative medicine. Nano Lett. 2019;19(4):2198-2206. https://doi.org/10.1021/acs.nanolett.9b00472
Shin K, Acri T, Geary S, Salem AK. Biomimetic mineralization of biomaterials using simulated body fluids for bone tissue engineering and regenerative medicine. Tissue Eng Part A. 2017;23(19-20):1169-1180. https://doi.org/10.1089/ten.tea.2016.0556
Xu M, Qin M, Cheng Y, Niu X, Kong J, Zhang X, Huang D, Wang H. Alginate microgels as delivery vehicles for cell-based therapies in tissue engineering and regenerative medicine. Carbohydr Polym. 2021;266:118128. https://doi.org/10.1016/j.carbpol.2021.118128
Liu S, Yu JM, Gan YC, Qiu XZ, Gao ZC, Wang H, Chen SX, Xiong Y, Liu GH, Lin SE, McCarthy A. Biomimetic natural biomaterials for tissue engineering and regenerative medicine: new biosynthesis methods, recent advances, and emerging applications. Mil Med Res. 2023;10(1):1-30. https://doi.org/10.1186/s40779-023-00448-w
Liu N, Ye X, Yao B, Zhao M, Wu P, Liu G, Zhuang D, Jiang H, Chen X, He Y, Huang S. Advances in 3D bioprinting technology for cardiac tissue engineering and regeneration. Bioact Mater. 2021;6(5):1388-1401. https://doi.org/10.1016/j.bioactmat.2020.10.021
Faramarzi N, Yazdi IK, Nabavinia M, Gemma A, Fanelli A, Caizzone A, Ptaszek LM, Sinha I, Khademhosseini A, Ruskin JN, Tamayol A. Patient‐specific bio-inks for 3D bioprinting of tissue engineering scaffolds. Adv Healthc Mater. 2018;7(11):1701347. https://doi.org/10.1002/adhm.201701347
Pang C, Ibrahim A, Bulstrode NW, Ferretti P. An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing. Int Wound J. 2017;14(3):450-459. https://doi.org/10.1111/iwj.12735
Savoji H, Godau B, Hassani MS, Akbari M. Skin tissue substitutes and biomaterial risk assessment and testing. Front Bioeng Biotechnol. 2018;6:86. https://doi.org/10.3389/fbioe.2018.00086
Goodarzi P, Falahzadeh K, Nematizadeh M, Farazandeh P, Payab M, Larijani B, Tayanloo Beik A, Arjmand B. Tissue-engineered skin substitutes. In: Cell Biology and Translational Medicine, Volume 3: Stem Cells, Biomaterials, and Tissue Engineering, pp.143-188. DOI: 10.1007/5584_2018_226
Gungor-Ozkerim PS, Inci I, Zhang YS, Khademhosseini A, Dokmeci MR. Bioinks for 3D bioprinting: an overview. Biomater Sci. 2018;6(5):915-946. https://doi.org/10.1039/C7BM00765E
Li X, Liu B, Pei B, Chen J, Zhou D, Peng J, Zhang X, Jia W, Xu T. Inkjet bioprinting of biomaterials. Chem Rev. 2020;120(19):10793-10833. https://doi.org/10.1021/acs.chemrev.0c00008
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Derechos de autor 2023 Geetika Madan Patel, Nayana Borah, Gaurav Kumar
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