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Two-stage bilateral subthalamotomy for patients with idiopathic Parkinson's disease

By
María Teresa Solomon Cardona ,
María Teresa Solomon Cardona

Centro Internacional de Restauración Neurológica (CIREN). La Habana, Cuba

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Julián Leonardo Gallo Rodríguez ,
Julián Leonardo Gallo Rodríguez

Centro Internacional de Restauración Neurológica (CIREN). La Habana, Cuba

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Yordanka Ricardo de la Fé ,
Yordanka Ricardo de la Fé

Centro Internacional de Restauración Neurológica (CIREN). La Habana, Cuba

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Hector Julio Piñera-Castro ,
Hector Julio Piñera-Castro

Universidad de Ciencias Médicas de La Habana, Facultad “Victoria de Girón”. La Habana, Cuba

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Juan Tejeiro Amador ,
Juan Tejeiro Amador

Centro Internacional de Restauración Neurológica (CIREN). La Habana, Cuba

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Raúl José Macías González ,
Raúl José Macías González

Centro Internacional de Restauración Neurológica (CIREN). La Habana, Cuba

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Abstract

Introduction: in the world there is sufficient experience with functional surgery for Parkinson's disease using the subthalamic nucleus approach, but mainly with the use of deep brain stimulation. Less experience exists in the use of ablative methods.
Objective: to evaluate the therapeutic effect, refinement in surgical target localization and safety of bilateral subthalamic subthalamotomy in two surgical times for the treatment of patients with idiopathic Parkinson's disease.
Methods: observational, analytical, cross-sectional study at CIREN (Havana, Cuba) between January 2018 and December 2020, in 10 patients. Variables related to general characteristics of patients and surgeries, therapeutic effect of the procedure, refinement of surgical target localization and safety of surgeries were analyzed.
Results: the motor condition of the patients improved (p < 0.0001) both in the off stage (70.9%) and on stage (74.7%). Target localization refinement reduced the number of paths (5.3 ± 2 vs. 3.4 ± 0.5, p = 0.03) and surgical time (87.6 ± 40.7 min vs. 53.6 ± 13.5 min, p = 0.01). A total of 10 adverse events occurred.
Conclusions: the procedure used has a beneficial and safe therapeutic effect on the motor condition of patients with idiopathic Parkinson's disease. The refinement of the localization of the surgical target allows a reduction in the number of paths and the surgical time.

How to Cite

1.
Solomon Cardona MT, Gallo Rodríguez JL, Ricardo de la Fé Y, Piñera-Castro HJ, Tejeiro Amador J, Macías González RJ. Two-stage bilateral subthalamotomy for patients with idiopathic Parkinson’s disease. Salud, Ciencia y Tecnología [Internet]. 2023 Sep. 10 [cited 2024 Jul. 20];3:578. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/578

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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