Universidad Técnica de Ambato. Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador
Universidad Técnica de Ambato. Facultad de Ciencias de la Salud, Carrera de Laboratorio Clínico. Ambato, Ecuador
Introduction: the average platelet volume is obtained from the blood count, considered as a low-cost and easily accessible biomarker, available in all medical units. It is considered a biomarker that indicates inflammation, thrombosis, and endothelial injury, while foreign studies have shown encouraging advances in diseases with prothrombotic and immunoinflammatory components.
Objective: to establish the relationship of mean platelet volume with hospital septic infections.
Methodology: information sources available in the Pubmed, Medicgraphic, and SciELO databases were consulted, as well as the Google Scholar search engine. Publications in both English and Spanish were included, with a maximum of 5 years prior to the topic of interest.
Results: Original articles were analyzed in which populations of neonates and adults with sepsis are analyzed. Populations of newborns reflected a high value of MPV in the first 24 hours, proving to be an early predictive marker in the diagnosis of neonatal sepsis, while population studies in adults reflected a much higher MPV in septic patients who later died. in relation to those who survived, being also considered a predictor of mortality.
Conclusions: it is evident that MPV is closely related to sepsis since it increases progressively during infection, constituting a biomarker for early prediction and poor prognosis in sepsis.
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