Efecto del ayuno intermitente sobre los niveles de proteína C reactiva y calprotectina en un paciente con colitis ulcerosa. Un reporte de caso.

Claudio Villota-Arcos; Angel Roco-Videla; Carolina Pino-Astorga; Daniela Mendoza-Puga; Mauricio Bittner; Tatiana  Corbeaux-Ascui; Raúl Aguilera-Eguía

doi:10.56294/saludcyt20241021

Case Report

Published: 2024-05-20

DOI: https://doi.org/10.56294/saludcyt20241021

Effect of intermittent fasting on C-reactive protein and calprotectin levels in a Patient with Ulcerative Colitis. A case report

Abstract

Introduction: Ulcerative colitis is a disease whose causes are multifactorial. Current therapies, such as monoclonal antibodies, present risks, prompting the search for non-pharmacological alternatives such as intermittent fasting. To detect inflammatory conditions, the levels of calprotectin and C-reactive protein are measured.
Objective: To evaluate the effects of intermittent fasting in a 34-year-old patient with ulcerative colitis, on the inflammatory markers calprotectin and C-reactive protein (CRP).
Clinical case: 34-year-old Caucasian woman diagnosed with ulcerative colitis in remission, she participated in an 8-week pilot study on intermittent fasting. After the intervention, it was observed that there were no significant changes in her PRC levels, however, calprotectin increased from 15 mg/kg to 1279 mg/kg, indicating an inflammatory bowel condition in the initial stage given that the patient was asymptomatic.
Conclusions: Calprotectin determination is a more appropriate marker to identify intestinal inflammation in early stages. Intermittent fasting could be a complementary therapeutic strategy to extend the periods of symptom remission in this disease.

Keywords:

ulcerative colitis,

C-reactive protein,

calprotectin,

How to Cite

Villota-Arcos C, Roco-Videla A, Pino-Astorga C, Mendoza-Puga D, Bittner M, Corbeaux-Ascui T, Aguilera-Eguía R. Effect of intermittent fasting on C-reactive protein and calprotectin levels in a Patient with Ulcerative Colitis. A case report. Salud, Ciencia y Tecnología [Internet]. 2024 May 20 [cited 2024 Jul. 27];4:1021. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/1021

Copyright Notice

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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