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Case Report

Effect of intermittent fasting on C-reactive protein and calprotectin levels in a Patient with Ulcerative Colitis. A case report

By
Claudio Villota-Arcos ,
Claudio Villota-Arcos

Universidad Bernardo O´Higgins, Escuela de Nutrición y Dietética, Facultad de Ciencias de la Salud. Santiago, Chile

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Angel Roco-Videla ,
Angel Roco-Videla

Universidad Arturo Prat. Iquique, Chile

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Carolina Pino-Astorga ,
Carolina Pino-Astorga

Universidad Bernardo O´Higgins, Escuela de Nutrición y Dietética, Facultad de Ciencias de la Salud. Santiago, Chile

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Daniela Mendoza-Puga ,
Daniela Mendoza-Puga

Integramédica, parte de BUPA, director médico ITR-IBB-ITA.Santiago, Chile

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Mauricio Bittner ,
Mauricio Bittner

Universidad Andrés Bello, Laboratorio de Microbiología y Biotecnología Oral, Facultad de Ciencias de la Vida. Santiago, Chile

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Tatiana Corbeaux-Ascui ,
Tatiana Corbeaux-Ascui

Fundación Oncoloop. Santiago, Chile

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Raúl Aguilera-Eguia ,
Raúl Aguilera-Eguia

Universidad Católica de la Santísima Concepción, Facultad de Medicina. Concepción, Chile

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Abstract

Introduction: Ulcerative colitis is a disease whose causes are multifactorial. Current therapies, such as monoclonal antibodies, present risks, prompting the search for non-pharmacological alternatives such as intermittent fasting. To detect inflammatory conditions, the levels of calprotectin and C-reactive protein are measured.
Objective: To evaluate the effects of intermittent fasting in a 34-year-old patient with ulcerative colitis, on the inflammatory markers calprotectin and C-reactive protein (CRP).
Clinical case: 34-year-old Caucasian woman diagnosed with ulcerative colitis in remission, she participated in an 8-week pilot study on intermittent fasting. After the intervention, it was observed that there were no significant changes in her PRC levels, however, calprotectin increased from 15 mg/kg to 1279 mg/kg, indicating an inflammatory bowel condition in the initial stage given that the patient was asymptomatic.
Conclusions: Calprotectin determination is a more appropriate marker to identify intestinal inflammation in early stages. Intermittent fasting could be a complementary therapeutic strategy to extend the periods of symptom remission in this disease.

How to Cite

1.
Villota-Arcos C, Roco-Videla A, Pino-Astorga C, Mendoza-Puga D, Bittner M, Corbeaux-Ascui T, Aguilera-Eguía R. Effect of intermittent fasting on C-reactive protein and calprotectin levels in a Patient with Ulcerative Colitis. A case report. Salud, Ciencia y Tecnología [Internet]. 2024 May 20 [cited 2024 Jun. 20];4:1021. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/1021

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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