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Influence of the use of psychotropic drugs on the increase of Escherichia coli resistance

By
Dayanara Tifane Zambrano Zambrano ,
Dayanara Tifane Zambrano Zambrano

Universidad Técnica de Ambato, Facultad de Laboratorio Clínico. Ambato, Ecuador

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Lourdes Gioconda Tabares Rosero ,
Lourdes Gioconda Tabares Rosero

Universidad Técnica de Ambato, Facultad de Laboratorio Clínico. Ambato, Ecuador

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Abstract

Introduction: Escherichia coli is one of the most investigated bacteria due to the diversity of impacts on human health; it can sometimes form new resistant strains through conjugation processes, becoming a real public health problem.
Objective: To evaluate the relationship between prolonged use of psychotropic drugs and increased antimicrobial resistance in Escherichia coli strains.
Methods: A comprehensive literature review was conducted using different databases of scientific importance; including 35 theses, research articles and reviews published in Spanish and English, from 2019 to 2023.
Results: Studies of patients under psychotropic treatment with tricyclic antidepressants and selective serotonin reuptake inhibitors for more than 3 months were analyzed; proving the appearance of dysbiosis in the intestinal microbiota.
Conclusion: The appearance of dysbiosis in the intestinal microbiota of patients under treatment with psychotropic drugs such as tricyclic antidepressants and selective serotonin reuptake inhibitors, causes a reduction in beneficial bacteria and favors the necessary environment for an increase in pathogenic gram-negative bacteria with resistant mutated strains, specifically Escherichia coli.

How to Cite

1.
Zambrano Zambrano DT, Tabares Rosero LG. Influence of the use of psychotropic drugs on the increase of Escherichia coli resistance. Salud, Ciencia y Tecnología [Internet]. 2023 Dec. 27 [cited 2024 Feb. 23];4:701. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/701

The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

 

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