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Salud, Ciencia y Tecnología Metaverse Basic and Applied Research Data & Metadata Interdisciplinary Rehabilitation Salud, Ciencia y Tecnología - Serie de Conferencias Community and Interculturality in Dialogue Seminars in Medical Writing and Education Health Leadership and Quality of Life Gamification and Augmented Reality Southern perspective / Perspectiva austral
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Published: 2024-02-09
DOI: https://doi.org/10.56294/saludcyt2024772

Environmental factors associated with cleft lip and palate in children treated at the William Soler Hospital

By
Julio Valcarcel Llerandi ,
Julio Valcarcel Llerandi

Hospital Pediátrico Universitario William Soler. La Habana. Cuba

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Estela Morales Peralta ,
Estela Morales Peralta

Centro Nacional de Genética Médica. La Habana, Cuba

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María del Carmen Fernández González ,
María del Carmen Fernández González

Instituto Cubano de Oftalmología Ramón Pando Ferrer. La Habana. Cuba

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Amparo Pérez Borrego ,
Amparo Pérez Borrego

Universidad de Ciencias Médicas de La Habana, Facultad de Ciencias Médicas Enrique Cabrera. La Habana, Cuba

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Abstract

Introduction: Cleft lip and palate is the most prevalent craniofacial congenital defect worldwide. It consists of a labial or palatal cleft, even a combination of both. It is currently known that cleft lip and palate have multifactorial causes, which include both genetic and environmental factors, which influence the first trimester of pregnancy. Objective: To describe environmental factors in patients with cleft lip and palate treated at the William Soler Pediatric Hospital, in the period between 2021 and 2022. Methodological design: Descriptive, cross-sectional and retrospective study in patients with a diagnosis of cleft lip and palate. The sample was characterized taking into account sex, type of fissure, maternal toxic habits, exposure to radiation, mechanical injuries and environmental toxins, drug consumption, as well as acute and chronic maternal diseases. Data collected during interrogation and physical examination were used. Results: isolated palatal clefts represented 50.5%. 13.7% of mothers smoked during the first trimester of pregnancy, while 10.5% consumed alcohol. High blood pressure (25%) was the most common maternal chronic disease while 41% were diagnosed with vaginal moniliasis. Conclusions: Isolated cleft palate and considerable tobacco and alcohol consumption among pregnant women predominated. Among the chronic diseases, there was a predominance of high blood pressure, the most frequent infectious diseases were vaginal moniliasis and urinary tract infections, and there was a high frequency of the consumption of clotrimazole and oral contraceptives.

Keywords:

Cleft lip,
cleft palate,
teratogens,
abnormalities,
drug induced,

How to Cite

1.
Valcarcel Llerandi J, Morales Peralta E, Fernández González M del C, Pérez Borrego A. Environmental factors associated with cleft lip and palate in children treated at the William Soler Hospital. Salud, Ciencia y Tecnología [Internet]. 2024 Feb. 9 [cited 2024 Jul. 26];4:772. Available from: https://revista.saludcyt.ar/ojs/index.php/sct/article/view/772

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The article is distributed under the Creative Commons Attribution 4.0 License. Unless otherwise stated, associated published material is distributed under the same licence.

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Vol. 4 (2024)
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